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Dr.-Ing. Patrick Diederich

Doktorand
patrick diederichHnw0∂kit edu

Engler-Bunte-Ring 3
Gebäude 40.12
76131 Karlsruhe


Lebenslauf und Publikationen

Scientific CV
08/2009 - now
Ph.D. student, Institute of Engineering in Life Sciences, KIT
09/2008 – 12/2008

Industriepraktikum bei Genentech Inc., San Francisco, USA
High throughput screening of chromatographic resins
Evaluation of an alternative method to design experiments

08/2008 – 09/2008

Hilfswissenschaftliche Tätigkeit: „In-silico-Analyse eines genetischen Algorithmus zur Prozessoptimierung“
Institut für Bio- und Lebensmitteltechnik, Universität Karlsruhe (TH)

01/2008 – 07/2008

Diplomarbeit: „Optimierung eines industriellen Aufreinigungs­prozesses für monoklonale Antikörper mittels intelligenten, roboterbasierten Hochdurchsatzverfahren“
Institut für Biotechnologie II, Forschungszentrum Jülich
Institut für Bio- und Lebensmitteltechnik, Universität Karlsruhe (TH)

05/2006 – 09/2006

Studienarbeit: “Fabrication of dense magnetic pellicular support customized for liquid magnetically stabilized fluidized bed adsorption”
Department of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, USA

10/2005 – 03/2006

Industriepraktikum bei Lonza AG, Visp, CH
Prozessentwicklung Fed-Batch Fermentation

10/2002 – 07/2008
Studium des Bioingenieurwesens, Universität Karlsruhe (TH)
Research Projects
 

Predictive Tools in Protein Chromatography: Extension and Optimization of a Molecular Modeling Approach

 

Publikationen

 
Poster
 

von Lieres, E.; Diederich, P.; Siudak, A.; Susanto, A.; Treier, K.; Hubbuch, J.
Optimization of High Throughput Process Optimization

Recovery XIII (Quebec), June 22–27, 2008.

 

Treier, K.; Diederich, P.; Susanto, A.; Siudak, A.; von Lieres, E.; Hubbuch, J.
High Throughput Downstream Process Development: Optimization of a Cation Exchange Chromatography Step

ISPPP (Baden-Baden), September 21-24, 2008.

 

P. Diederich, F. Hämmerling, J. Hubbuch (2011).
High Throughput Screening of Aqueous Two-Phase Systems for the Purification of Hen’s Egg White Protein Avidin;
GVC/DECHEMA – Congress, Potsdam, GER

 

P. Diederich, J. Hubbuch (2011).
Error Estimation for High Throughput Column Chromatography Processes on a Liquid Handling Station;
European Congress on Applied Biotechnology, Berlin, GER

 

P. Diederich, J. Hubbuch (2010).
Fast Analytical Techniques to complement High Throughput Downstream Process Development- Case Study: Analysis of Hen Egg Proteins using LabChip® and (U)HPLC;
HTPD10, Krakau, Poland

 
 
Paper
 

Patrick Diederich, Sigrid K. Hansen, Stefan A. Oelmeier, Bianca Stolzenberger, Jürgen Hubbuch.
A Sub-Two Minutes Method for Monoclonal Antibody-Aggregate Quantification using Parallel Interlaced Size Exclusion High Performance Liquid Chromatography,

Journal of Chromatography A, 1218(50), pp. 9010-9018 – 2011.

 

K. Treier, S. Hansen, C. Richter, P. Diederich, J. Hubbuch, P. Lester.
High-throughput methods for miniaturization and automation of monoclonal antibody purification processes,
Biotechnology Progress, 28 (2012) 723-732

 

Katrin Treier, Annette Berg, Patrick Diederich, Katharina Lang, Anna Osberghaus, Florian Dismer, Jürgen Hubbuch,
Examination of a genetic algorithm for the application in high-throughput downstream process development,
Biotechnology Journal (2012), 7(10), 1203-1215



Presentations
 

P. Diederich, A. Osberghaus, J. Hubbuch (2012).
Error Analysis & Characterization of µL-scale Column Chromatography performed on Liquid Handling Stations;
HTPD12, Avignon, France

P. Diederich, S. K. Hansen, B. Maiser, N. Schnabel (2011).
A-Mab: a Case Study in Bioprocess Development
Downstream Days Summer School, Wetter a. d. Ruhr, Germany, 2011

P. Diederich, A. Osberghaus, J. Hubbuch (2012).
Aspects on Data Quality of High Throughput Column Chromatography; 8th international PhD Seminar on Preparative Chromatography,
Freudenstadt-Lauterbad, Germany

P. Diederich, J. Hubbuch (2011).
High Throughput Process Development.
GE healthcare/Sanofi-Aventis Äkta UserClub, Frankfurt a. M., Germany