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Morgenstern

Dr.-Ing. Josefine Morgenstern

Postdoc
room: R. 208
phone: +49 721 608 47524
fax: +49 721 608 46240
josefine morgensternJnk4∂kit edu

Fritz-Haber-Weg 2
Gebäude 30.44
76131 Karlsruhe



CV and Publications

Scientific CV

04/2014 to date Ph.D. student at Institute of Process Engineering in Life Sciences, Biomolecular Separation Engineering (MAB), Karlsruhe Institute for Technology (KIT)
11/2013 - 03/2014 Student assistant at MAB, KIT
12/2012 - 06/2013 Diploma Thesis at MAB, KIT: "‘Determination of protein phase diagrams as a basis for the analysis of protein secondary structures via Fourier transform infrared spectroscopy"’
04/2011 - 05/2012 Student research project at Institute of Thermal Process Engineering (TVT), KIT: "‘Stabilisation of precipitated barium sulfate nanosuspensions"’
10/2010 - 03/2011 Internship at Lonza Braine, Braine-L’Alleud, Belgium
10/2009 - 09/2010 Student assistant at Institute of Chemical Process Engineering (CVT), KIT
10/2007 - 06/2013 Studies of Life Science Engineering, KIT



 

Research Projects

Phase behaviour and stability of enzymes for industrial applications



 

Publications

Paper

J. Morgenstern, P.Baumann, C. Brunner, J. Hubbuch, Effect of PEG molecular weight and PEGylation degree on the physical stability of PEGylated lysozyme, International Journal of Pharmaceutics 519 (2017) 408-417, http://www.sciencedirect.com/science/article/pii/S0378517317300492.

J. Morgenstern, M. Busch, P. Baumann, J. Hubbuch, Quantification of PEGylated proteases with varying degree of conjugation in mixtures: An analytical protocol combining protein precipitation and capillary gel electrophoresis, Journal of Chromatography A 1462 (2016) 153-164, http://www.sciencedirect.com/science/article/pii/S0021967316310196.

L. Galm, J. Morgenstern, J. Hubbuch, Manipulation of lysozyme phase behavior by additives as function of conformational stability, International Journal of Pharmaceutics 494 (2015) 370-380, http://www.sciencedirect.com/science/article/pii/S0378517315301393.

K. Baumgartner, L. Galm, J. Nötzold, H. Sigloch, J. Morgenstern, K. Schleining, S. Suhm, S.A. Oelmeier, J. Hubbuch, Determination of protein phase diagrams by microbatch experiments: Exploring the influence of precipitants and pH, International Journal of Pharmaceutics 479 (2015) 28-40, http://www.sciencedirect.com/science/article/pii/S0378517314009247.
 

Präsentationen

J. Morgenstern, J. Hubbuch, Characterization and manipulation of protein stabilities for downstream process development, Forum Prozesschromatographie, Griesheim, Germany, 11.2016.
 

Poster

J. Morgenstern, L. Galm, P. Baumann, C. Brunner, J. Hubbuch, Characterization and manipulation of protein stabilities for downstream process development, 36th International Symposium on the Separation of Proteins, Peptides and Polynucleotides (ISPPP), Salzburg, Österreich ,11.2016.

R. Kügler, J. Morgenstern, L. Metzger, M. Kucher, M. Kind, Fällungskristallisation von Bariumsulfat - Vermischung der Edukte und Stabilisierung von Nanosuspensionen, ProcessNet Fachausschuss Kristallisation, Wittenberg, Deutschland, 03. 2012, https://www.tvt.kit.edu/downloads/Kuegler_Poster_FAWittenberg2012.pdf.

R. Kügler, J. Morgenstern, M. Kucher, M. Kind, Comparison of different impinging jet mixers and stabilisation of precipitated barium sulfate nanosuspensions, 18th International Symposium on Industrial Crystallization (ISIC 18), Zurich, Switzerland, 09. 2011, https://www.tvt.kit.edu/downloads/Kuegler_Poster_ISIC.pdf.