Lebenslauf und Publikationen
|10/2014 - now||Research associate and PhD candidate at the Institute of Engineering in Life Sciences, Karlsruhe Institute for Technology|
|02/2014 - 08/2014||Co-op in the Purification Development department at Genentech Inc., South San Francisco, USA: Mechanistic modeling of ion exchange chromatography steps for process characterization and validation|
|10/2012 - 08/2013||Visiting Student Researcher in the Department of Neurology and Neurological Sciences, Steinman lab, Stanford University School of Medicine, USA: The role of aB-crystallin in oligodendrocytes|
|08/2012 - 10/2012||Intern at Glatt Ingenieurtechnik GmbH, Weimar, Germany: Development of a GMP framework for continuous fluid bed dryers|
|04/2012 – 06/2012||Intern at the Institute for Virology and Immunobiology, Berberich lab, University of Würzburg: Research on terminal B cell differentiation|
|02/2012 – 04/2012||Graduate research project at the Institute of Toxicology and Genetics, Grabher lab, Karlsruhe Institute of Technology: In situ hybridization analysis of gene expression of putative target genes of anti-inflammatory drugs upon chemically induced inflammation in zebrafish|
|07/2011 - 09/2013||Graduate studies, Biochemical and Business Engineering, Karlsruhe Institute of Technology|
|02/2011 – 06/2011||Bachelor thesis in the Department of Physiological Chemistry, Gaubatz lab, University of Würzburg: Analysis of GAS2L3 phosphorylation sites and their influence on GAS2L3 protein stability and cellular localization|
|10/2008 - 07/2011||Undergraduate Studies, Biomedicine, University of Würzburg|
|10/2005 - 09/2008||Undergraduate Studies, Business Engineering, Karlsruhe Institute of Technology|
Characterization and modeling of novel chromatography media and single use systems
O. Ötes, J. Winderl, J. Hubbuch, H. Flato, F. Capito, Feasibility of using continuous chromatography in downstream processing: Comparison of costs and product quality for a hybrid process vs. a conventional batch process, J. Biotechnol. 259 (2017) 213-220, https://doi.org/10.1016/j.jbiotec.2017.07.001.
J. Winderl, T. Hahn, J. Hubbuch, A mechanistic model of ion-exchange chromatography on polymer fiber stationary phases, J. Chromatogr. A 1475 (2016) 18-30, http://dx.doi.org/10.1016/j.chroma.2016.10.057.
R. Schubert, Y. Hu, G. Kumar, S. Szeto, P. Abraham, J. Winderl, J. Guthridge, G. Pardo, J. Dunn, L. Steinman, R. Axtell, IFN-β treatment requires B cells for efficacy in neuroautoimmunity, J. Immunol. 194 (2015) 2110-6, http://dx.doi.org/10.4049/jimmunol.1402029.
H. Kuipers, J. Yoon, J. Winderl, J. van Horssen, M. Han, T. Palmer, L. Steinman, Differential phosphorylation of alpha B-crystallin in astrocytes and oligodendrocytes suggests a diversity in its biological function, J. Neuroimmunol. 275 (2014) 157-158, http://dx.doi.org/10.1016/j.jneuroim.2014.08.423.
J. Winderl, T. Hahn, J. Hubbuch, Mechanistic modeling of fiber-based ion exchange adsorbents, 13th International PhD Seminar on Chromatographic Separation Science (SoCSS 2017), Annweiler am Trifels, Germany, February 26-28, 2017.
H. Kuipers, J. Yoon, J. Winderl, J. van Horssen, M. Han, T. Palmer, L. Steinman, Differential phosphorylation of alpha B-crystallin in astrocytes and oligodendrocytes suggests a diversity in its biological function, 12th International Congress of Neuroimmunology (ISNI), Mainz, Germany, November 9-13, 2014.
J. Winderl, E. Neumann, J. Hubbuch, Exploration of Fiber-based Cation Exchange Adsorbents for the Removal of Monoclonal Antibody Aggregates, 30th International Symposium on Preparative and Process Chromatography, Philadelphia, USA, July 16-19, 2017.
J. Winderl, T. Hahn, J. Hubbuch, Mechanistic modeling of fiber-based adsorbents for ion exchange chromatography, Himmelfahrtstagung 2017: Models for Developing and Optimising Biotech Production, Neu-Ulm, Germany, May 22-24, 2017.
C. Williams, J. Winderl, T. Hahn, Mechanistic Modeling of a Cation Exchange Chromatography Step, High-Throughput Process Development 2014 (HTPD), Siena, Italy, October 6-9, 2014.