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Johannes Winderl

Dipl.-Wi.-Ing. Johannes Winderl

PhD student
room: R. 102
phone: +49 721 608 46227
fax: +49 721 608 46240
johannes winderlHvo4∂kit edu

Fritz-Haber-Weg 7
Gebäude 30.91
76131 Karlsruhe



Lebenslauf und Publikationen

Scientific CV

10/2014 - now Research associate and PhD candidate at the Institute of Engineering in Life Sciences, Karlsruhe Institute for Technology
02/2014 - 08/2014 Co-op in the Purification Development department at Genentech Inc., South San Francisco, USA: Mechanistic modeling of ion exchange chromatography steps for process characterization and validation
10/2012 - 08/2013 Visiting Student Researcher in the Department of Neurology and Neurological Sciences, Steinman lab, Stanford University School of Medicine, USA: The role of aB-crystallin in oligodendrocytes
08/2012 - 10/2012 Intern at Glatt Ingenieurtechnik GmbH, Weimar, Germany: Development of a GMP framework for continuous fluid bed dryers
04/2012 – 06/2012 Intern at the Institute for Virology and Immunobiology, Berberich lab, University of Würzburg: Research on terminal B cell differentiation
02/2012 – 04/2012 Graduate research project at the Institute of Toxicology and Genetics, Grabher lab, Karlsruhe Institute of Technology: In situ hybridization analysis of gene expression of putative target genes of anti-inflammatory drugs upon chemically induced inflammation in zebrafish
07/2011 - 09/2013 Graduate studies, Biochemical and Business Engineering, Karlsruhe Institute of Technology
02/2011 – 06/2011 Bachelor thesis in the Department of Physiological Chemistry, Gaubatz lab, University of Würzburg: Analysis of GAS2L3 phosphorylation sites and their influence on GAS2L3 protein stability and cellular localization
10/2008 - 07/2011 Undergraduate Studies, Biomedicine, University of Würzburg
10/2005 - 09/2008 Undergraduate Studies, Business Engineering, Karlsruhe Institute of Technology



 

Research Projects

Characterization and modeling of novel chromatography media and single use systems



 

Publications

Paper

J. Winderl, T. Hahn, J. Hubbuch, A mechanistic model of ion-exchange chromatography on polymer fiber stationary phases, J. Chromatogr. A 1475 (2016) 18-30, http://dx.doi.org/10.1016/j.chroma.2016.10.057.

R. Schubert, Y. Hu, G. Kumar, S. Szeto, P. Abraham, J. Winderl, J. Guthridge, G. Pardo, J. Dunn, L. Steinman, R. Axtell, IFN-β treatment requires B cells for efficacy in neuroautoimmunity, J. Immunol. 194 (2015) 2110-6, http://dx.doi.org/10.4049/jimmunol.1402029.

H. Kuipers, J. Yoon, J. Winderl, J. van Horssen, M. Han, T. Palmer, L. Steinman, Differential phosphorylation of alpha B-crystallin in astrocytes and oligodendrocytes suggests a diversity in its biological function, J. Neuroimmunol. 275 (2014) 157-158, http://dx.doi.org/10.1016/j.jneuroim.2014.08.423.
 

Talks

J. Winderl, T. Hahn, J. Hubbuch, Mechanistic modeling of fiber-based ion exchange adsorbents, 13th International PhD Seminar on Chromatographic Separation Science (SoCSS 2017), Annweiler am Trifels, Germany, February 26-28, 2017.

H. Kuipers, J. Yoon, J. Winderl, J. van Horssen, M. Han, T. Palmer, L. Steinman, Differential phosphorylation of alpha B-crystallin in astrocytes and oligodendrocytes suggests a diversity in its biological function, 12th International Congress of Neuroimmunology (ISNI), Mainz, Germany, November 9-13, 2014.
 

Poster

C. Williams, J. Winderl, T. Hahn, Mechanistic Modeling of a Cation Exchange Chromatography Step, High-Throughput Process Development 2014 (HTPD), Siena, Italy, October 6-9, 2014.