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Katha Bauer

Dr.-Ing. Katharina Bauer

PhD student
room: R. 104
phone: +49 721 608 47525
fax: +49 721 608 46240
katharina bauerUbb5∂kit edu

Engler-Bunte-Ring 3
Gebäude 40.12
76131 Karlsruhe



CV and Publications

Scientific CV

12/2012 - now PhD student
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)
01/2012 - 07/2012 Diploma thesis: „Characterization of protein interactions for protein crystallization using static light scattering“
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)
08/2011 - 11/2011 Scientific Assistant
Institute for Technical Thermodynamics and Refrigeration, Karlsruhe Institute for Technology (KIT)
02/2011 - 07/2011 Studies in chemical engineering
Ecole supérieure de chimie physique électronique de Lyon (CPE Lyon), France
10/2010 - 05/2011 Student Research Project: “Studies on the reaction of N-heterocyclic carbenes from ionic liquids with benzaldehyde in supercritical CO2
Institute for Technical Thermodynamics and Refrigeration & Institute of Organic Chemistry, Karlsruhe Institute for Technology (KIT)
10/2009 - 03/2010 Internship at Cognis GmbH, Düsseldorf
Production of sophorose lipids by fermentation of candida bombicola, studies on the synthesis of sugar esters
12/2008 - 05/2009 Scientific Assistant
Institute of Process Engineering in Life Sciences, Section III: Bioprocess Engineering , Karlsruhe Institute of Technology (KIT)
10/2006 - 08/2012 Studies of Bioengineering at Karlsruhe Institute of Technology (KIT)



 

Research Projects

Aggregation tendency of biopharmaceutical products and the rheological behavior of highly concentrated solutions.



 

Publications

Paper

N. Rakel, L. Galm, K.C. Bauer, J. Hubbuch, Influence of macromolecular precipitants on phase behavior of monoclonal antibodies, Biotechnology Process 31(1) (2015) 145-153, http://onlinelibrary.wiley.com/doi/10.1002/btpr.2027/abstract.

N. Rakel, K.C. Bauer, L. Galm, J. Hubbuch, From Osmotic Second Virial Coefficient (B22) to Phase Behavior of a Monoclonal Antibody, Biotechnology Process 31(2) (2015) 438-451, http://onlinelibrary.wiley.com/doi/10.1002/btpr.2065/abstract.

S. Amrhein, K.C. Bauer, L. Galm, J. Hubbuch, Non-invasive high throughput approach for protein hydrophobicity determination based on surface tension, Biotechnology and Bioengineering 112(12) (2015) 2485-2494, http://onlinelibrary.wiley.com/doi/10.1002/bit.25677/abstract.

M.-T. Schermeyer, H. Sigloch, K.C. Bauer, C. Oelschlaeger, J. Hubbuch, Squeeze flow rheometry as a novel tool for the characterization of highly concentrated protein solutions, Biotechnology and Bioengineering 113(3) (2016) 576-587, http://onlinelibrary.wiley.com/doi/10.1002/bit.25834/abstract.

K.C. Bauer, M.-T. Schermeyer, J. Seidel, J. Hubbuch, Impact of polymer surface characteristics on the microrheological measurement quality of protein solutions - a tracer particle screening, International Journal of Pharmaceutics 2016, in press, http://www.sciencedirect.com/science/article/pii/S0378517316302563.
 

Talks

S. Amrhein, K.C. Bauer, L. Galm, M.-T. Schermeyer, J. Hubbuch, Predictive Approaches for Protein Phase Behavior, Recovery of Biological Products Conference XVI, Rostock, Germany, July 27-31, 2014.

K.C. Bauer, M.-T. Schermeyer, M. Göbel, M.-L. Schwab, J. Hubbuch, Characterizing phase behavior of highly concentrated protein solutions by dynamic light scattering, Biological and Pharmaceutical Complex Fluids II: Novel Trends in Characterizing Interactions, Microstructure and Rheology, Durham, NC, USA, August 10-14, 2014.

K.C. Bauer, M.-T. Schermeyer, M. Göbel, M.-L. Schwab, J. Hubbuch, Concentration dependent changes in protein diffusion as an approach to characterize the stability and viscosity of concentrated protein solutions, 3rd European Congress of Applied Biotechnology, Nice, France, September 27 - October 1, 2015.