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Matthias Rüdt

MSc Matthias Rüdt

PhD student
room: R. 107
phone: +49 721 608 47534
fax: +49 721 608 46240
matthias ruedtKxi7∂kit edu

Fritz-Haber-Weg 7
Gebäude 30.91
76131 Karlsruhe

CV and Publications

Scientific CV

01/2015 - now PhD student at the Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)
01/2014 - 10/2014 Scientist in Tech. Dev. in Downstream-Processing at Lek Pharmaceuticals d.d. (Sandoz), Slovenia
04/2013 - 12/2013 Internship on Model-based Chromatography Development in the Biologics Downstream-Processing Group, Novartis Pharma, Switzerland
03/2012 - 09/2012 Master thesis titled Studies on Multilayer Micropost Arrays in the Microsystems Group at Stanford University, California, USA
09/2011 - 02/2013 Master studies in biotechnology at the ETH Zürich, Switzerland
09/2010 - 08/2011 Bachelor studies in biotechnology at ETH Zürich, Switzerland
09/2008 - 08/2010 Basic studies in Chemistry at ETH Zürich, Switzerland


Research Projects

Development and application of chemometric methods for liquid chromatography.




M. Rüdt, T. Briskot, J. Hubbuch, Advances in downstream processing of biologics - Spectroscopy: An emerging process analytical technology, J. Chromatogr. A, accepted.

M. Rüdt, N. Brestrich, L. Rolinger, J. Hubbuch, Real-time monitoring and control of the load phase of a protein A capture step, Biotechnology and bioengineering, in press, http://dx.doi.org/10.1002/bit.26078.

M. Rüdt, F. Gillet, S. Heege, J. Hitzler, B. Kalbfuss, B. Guélat, Combined Yamamoto approach for simultaneous estimation of adsorption isotherm and kinetic parameters in ion-exchange chromatography, J. Chromatogr. A 1413 (2015) 68-76, http://dx.doi.org/10.1016/j.chroma.2015.08.025.


M. Rüdt, N. Brestrich, D. Büchler, L. Rolinger, A. Sanden, J. Hubbuch, PAT for preparative chromatography of proteins: Real-time monitoring of a capture and polishing step, SPICA 2016, Vienna, Austria, 11. October 2016.

G. Wang, T. Briskot, M. Rüdt, J. Hubbuch, Simulated Periodic Counter-Current Chromatography (sPCCC) – a scale-down model for multicolumn continuous chromatography process development, SPICA 2016, Vienna, Austria, 12. October 2016.

M. Rüdt, N. Brestrich, J. Hubbuch, Spectral deconvolution of chromatograms with PLS models and calibration-free methods, ACS Spring Meeting 2016, San Diego, California, 14th March 2016.


N. Brestrich, M. Rüdt, L. Rolinger, J. Hubbuch, Application of PAT in chromatography: from capture to polishing, Recovery of Biological Products XVII, Bermuda, 20th June 2016.

M. Rüdt, N. Brestrich, J. Hubbuch, Spectral deconvolution of chromatograms without offline analytics, Integrated Continuous Bioprocessing (ICB) 2, Berkeley, Kalifornien, USA, 2nd November 2015.