|01/2015 - now||PhD student at the Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)|
|01/2014 - 10/2014||Scientist in Tech. Dev. in Downstream-Processing at Lek Pharmaceuticals d.d. (Sandoz), Slovenia|
|04/2013 - 12/2013||Internship on Model-based Chromatography Development in the Biologics Downstream-Processing Group, Novartis Pharma, Switzerland|
|03/2012 - 09/2012||Master thesis titled Studies on Multilayer Micropost Arrays in the Microsystems Group at Stanford University, California, USA|
|09/2011 - 02/2013||Master studies in biotechnology at the ETH Zürich, Switzerland|
|09/2010 - 08/2011||Bachelor studies in biotechnology at ETH Zürich, Switzerland|
|09/2008 - 08/2010||Basic studies in Chemistry at ETH Zürich, Switzerland|
Development and application of chemometric methods for liquid chromatography.
M. Rüdt, T. Briskot, J. Hubbuch, Advances in downstream processing of biologics - Spectroscopy: An emerging process analytical technology, J. Chromatogr. A, accepted.
M. Rüdt, N. Brestrich, L. Rolinger, J. Hubbuch, Real-time monitoring and control of the load phase of a protein A capture step, Biotechnology and bioengineering, in press, http://dx.doi.org/10.1002/bit.26078.
M. Rüdt, F. Gillet, S. Heege, J. Hitzler, B. Kalbfuss, B. Guélat, Combined Yamamoto approach for simultaneous estimation of adsorption isotherm and kinetic parameters in ion-exchange chromatography, J. Chromatogr. A 1413 (2015) 68-76, http://dx.doi.org/10.1016/j.chroma.2015.08.025.
M. Rüdt, N. Brestrich, D. Büchler, L. Rolinger, A. Sanden, J. Hubbuch, PAT for preparative chromatography of proteins: Real-time monitoring of a capture and polishing step, SPICA 2016, Vienna, Austria, 11. October 2016.
G. Wang, T. Briskot, M. Rüdt, J. Hubbuch, Simulated Periodic Counter-Current Chromatography (sPCCC) – a scale-down model for multicolumn continuous chromatography process development, SPICA 2016, Vienna, Austria, 12. October 2016.
M. Rüdt, N. Brestrich, J. Hubbuch, Spectral deconvolution of chromatograms with PLS models and calibration-free methods, ACS Spring Meeting 2016, San Diego, California, 14th March 2016.
N. Brestrich, M. Rüdt, L. Rolinger, J. Hubbuch, Application of PAT in chromatography: from capture to polishing, Recovery of Biological Products XVII, Bermuda, 20th June 2016.
M. Rüdt, N. Brestrich, J. Hubbuch, Spectral deconvolution of chromatograms without offline analytics, Integrated Continuous Bioprocessing (ICB) 2, Berkeley, Kalifornien, USA, 2nd November 2015.