Wöll

Dr.-Ing. Anna Katharina Wöll

  • Fritz-Haber-Weg 2
    Gebäude 30.44
    76131 Karlsruhe

CV and Publications

Scientific CV

04/2016 - now PhD student at the Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)
 
12/2015 - 02/2016 Scientific assistant: stability research of highly concentrated monoclonal antibody solutions with the help of rheological measurements and structural anlaysis
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT
 
05/2015 - 11/2015 Master thesis: Comprehensive study on mAb phase behavior and solution characteristics with the help of rheological methods, dynamic light and fluorescence measurements
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT in cooperation with Synthon Biopharmaceuticals BV Nijmegen, Netherlands
 
07/2014 - 03/2015 Research assistant: mentoring of students and protein viscosity studies
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT
 
10/2013 - 03/2014 Internship at Sartorius Stedim Biotech GmbH
Characterization of virus filter units for application in down scale processes
 
04/2013 - 09/2013 Bachelor thesis: Examination of α-Lactalbumin phase behavior with the focus on isoeletric precipitation
Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT
 
12/2010 - 12/2012 Research assistant: chemical, toxicological, microbiological testing, groundwater sampling and luminescent bacteria inhibition test
Water Technology Center Karlsruhe (TZW)
 
10/2010 - 11/2015 Studies of Bioengineering at Karlsruhe Institute of Technology (KIT)



 

Research Projects

Protein stability studies considering behavior at low temperatures.



 

Publications

Articles

K.C. Bauer, S. Suhm, A.K. Wöll, J. Hubbuch, Impact of additives on the formation of protein aggregates and viscosity in concentrated protein solutions, Journal of Pharmaceutics (2016), https://doi.org/10.1016/j.ijpharm.2016.11.009

M.-T. Schermeyer, A.K. Wöll, B. Kokke, M. Eppink, J. Hubbuch, Characterization of highly concentrated antibody solution - A toolbox for the description of protein long-term solution stability, Journal mAbs (2017), https://doi.org/10.1080/19420862.2017.1338222

A.K. Wöll, J. Schütz, J. Zabel, J. Hubbuch Analysis of phase behavior and morphology during freeze-thaw applications, Journal of Pharmaceutics (2018), https://doi.org/10.1016/j.ijpharm.2018.11.047
 

Talks

A. Wöll, M. Desombre, L. Enghauser, J. Hubbuch, Influence of Different Freeze and Thaw Ramps on the Phase Behavior of Lysozyme from Chicken Egg White, ACS Spring Meeting 2018, New Orleans, 22. März 2018