CV and Publications

Scientific CV

09/2016 - now	PhD student Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)
01/2016 - 06/2016	Master thesis: Establishing conceptual designs for distributed manufacturing of CAR T cell therapies Biochemical Engineering Department, University College London (UCL) in cooperation with the Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)
10/2011 - 08/2015	Various jobs as scientific assistant: Tutorial in chemistry and mechanics, Mentoring of a lab course in biopharmaceutical process engineering and research assistant for optimization of cultivation experiments in E.coli and high-throughput screenings for protein solubility and aqueous two phase system partitioning of viral proteins Institutes of the Karlsruhe Institute of Technology (KIT)
09/2014 - 02/2015	Internship: Automation of methods for liquid handling of protein solutions; development of methods to assess solution viscosity of highly-concentrated protein solutions Novartis AG, Basel, Switzerland
06/2013 - 11/2013	Bachelor thesis: Establishment of the expression of the murine polyomavirus protein VP1 in E.coli and development of an integrated purification process using robot-based high-throughput methods Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute for Technology (KIT)
10/2010 - 06/2016	Studies of Bioengineering Karlsruhe Institute of Technology (KIT)

Research Projects

Response in dispersity, structure and phase behavior of virus-like particles (VLPs) under chemical and mechanical strain and varying antigen epitopes.

Publications

Paper

C. Ladd Effio, P. Baumann, C. Weigel, P. Vormittag, A. Middelberg, J. Hubbuch, High-throughput process development of an alternative platform for the production of virus-like particles in Escherichia coli, J. Biotechnol. 219 (2016) 7-19, http://dx.doi.org/10.1016/j.jbiotec.2015.12.018.

P. Vormittag, R. Gunn, S. Ghorashian, F. S. Veraitch, A guide to manufacturing CAR T cell therapies, Current Opinion in Biotechnology 53 (2018), 164-181, https://doi.org/10.1016/j.copbio.2018.01.025

M. E. Klijn, P. Vormittag, N. Bluthardt, J. Hubbuch. High-throughput computational pipeline for 3-D structure preparation and in silico protein surface property screening: A case study on HBcAg dimer structures, International Journal of Pharmaceutics, 2019, 563, 337 - 346, https://doi.org/10.1016/j.ijpharm.2019.03.057

M. Rüdt, P. Vormittag, N. Hillebrandt, J. Hubbuch. Process monitoring of virus-like particle reassembly by diafiltration with UV/Vis spectroscopy and light scattering, Biotechnology and Bioengineering, https://doi.org/10.1002/bit.26935