Dr.-Ing. Josefine Morgenstern
- Postdoc
- room: R. 208
- phone: +49 721 608 47524
- fax: +49 721 608 46240
- josefine morgenstern ∂ kit edu
Fritz-Haber-Weg 2
Gebäude 30.44
76131 Karlsruhe
CV and Publications
Scientific CV
04/2014 to date | Ph.D. student at Institute of Process Engineering in Life Sciences, Biomolecular Separation Engineering (MAB), Karlsruhe Institute for Technology (KIT) |
11/2013 - 03/2014 | Student assistant at MAB, KIT |
12/2012 - 06/2013 | Diploma Thesis at MAB, KIT: "‘Determination of protein phase diagrams as a basis for the analysis of protein secondary structures via Fourier transform infrared spectroscopy"’ |
04/2011 - 05/2012 | Student research project at Institute of Thermal Process Engineering (TVT), KIT: "‘Stabilisation of precipitated barium sulfate nanosuspensions"’ |
10/2010 - 03/2011 | Internship at Lonza Braine, Braine-L’Alleud, Belgium |
10/2009 - 09/2010 | Student assistant at Institute of Chemical Process Engineering (CVT), KIT |
10/2007 - 06/2013 | Studies of Life Science Engineering, KIT |
Research Projects
Phase behaviour and stability of enzymes for industrial applications
Publications
Paper
J. Morgenstern, P.Baumann, C. Brunner, J. Hubbuch, Effect of PEG molecular weight and PEGylation degree on the physical stability of PEGylated lysozyme, International Journal of Pharmaceutics 519 (2017) 408-417, http://www.sciencedirect.com/science/article/pii/S0378517317300492.
J. Morgenstern, M. Busch, P. Baumann, J. Hubbuch, Quantification of PEGylated proteases with varying degree of conjugation in mixtures: An analytical protocol combining protein precipitation and capillary gel electrophoresis, Journal of Chromatography A 1462 (2016) 153-164, http://www.sciencedirect.com/science/article/pii/S0021967316310196.
L. Galm, J. Morgenstern, J. Hubbuch, Manipulation of lysozyme phase behavior by additives as function of conformational stability, International Journal of Pharmaceutics 494 (2015) 370-380, http://www.sciencedirect.com/science/article/pii/S0378517315301393.
K. Baumgartner, L. Galm, J. Nötzold, H. Sigloch, J. Morgenstern, K. Schleining, S. Suhm, S.A. Oelmeier, J. Hubbuch, Determination of protein phase diagrams by microbatch experiments: Exploring the influence of precipitants and pH, International Journal of Pharmaceutics 479 (2015) 28-40, http://www.sciencedirect.com/science/article/pii/S0378517314009247.
Präsentationen
J. Morgenstern, J. Hubbuch, Characterization and manipulation of protein stabilities for downstream process development, Forum Prozesschromatographie, Griesheim, Germany, 11.2016.
Poster
J. Morgenstern, L. Galm, P. Baumann, C. Brunner, J. Hubbuch, Characterization and manipulation of protein stabilities for downstream process development, 36th International Symposium on the Separation of Proteins, Peptides and Polynucleotides (ISPPP), Salzburg, Österreich ,11.2016.
R. Kügler, J. Morgenstern, L. Metzger, M. Kucher, M. Kind, Fällungskristallisation von Bariumsulfat - Vermischung der Edukte und Stabilisierung von Nanosuspensionen, ProcessNet Fachausschuss Kristallisation, Wittenberg, Deutschland, 03. 2012, https://www.tvt.kit.edu/downloads/Kuegler_Poster_FAWittenberg2012.pdf.
R. Kügler, J. Morgenstern, M. Kucher, M. Kind, Comparison of different impinging jet mixers and stabilisation of precipitated barium sulfate nanosuspensions, 18th International Symposium on Industrial Crystallization (ISIC 18), Zurich, Switzerland, 09. 2011, https://www.tvt.kit.edu/downloads/Kuegler_Poster_ISIC.pdf.