Dr.-Ing. Sebastian Andris
- PhD student
- room: R. 201
- phone: +49 721 608 46241
- fax: +49 721 608 46240
- sebastian andris ∂ kit edu
Fritz-Haber-Weg 2
Gebäude 30.44
76131 Karlsruhe
CV and Publications
Scientific CV
01/2016 - Now | Ph.D. student at the Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT) |
01/2015 - 7/2015 | Internship at MedImmune, LLC, Gaithersburg, MD, USA Protein conjugation and HPLC assay development |
08/2014 - 12/2014 | Research assistant: Process Analytical Technology (PAT) Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT |
11/2013 - 06/2014 | Diploma thesis: Modeling of protein precipitation with polyethylene glycol (PEG) through quantitative structure-property relationships (QSPR) Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT |
04/2013 - 09/2013 | Student assistant: Microfluidics on Liquid Handling Stations (LHS) Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT |
06/2012 - 01/2013 | Seminar thesis: Establishment and validation of a microfluidic chip for high-throughput photometric analysis on a liquid handling robot Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT |
10/2011 - 03/2012 | Internship at DOW Chemical Ibérica, S.L., Tarragona, Spain Reverse Osmosis technology development for industrial water applications |
10/2008 - 06/2014 | Studies in Life Science Engineering, Karlsruhe Institute of Technology (KIT) |
Research Projects
High Throughput approaches for multi-step protein conjugation processes; characterization and modeling of conjugation processes; investigation of pseudo-payloads for the development of conjugation processes.
Publications
Paper
Andris S, Rüdt M, Rogalla J, Wendeler M, Hubbuch J. Monitoring of antibody-drug conjugation reactions with UV/Vis spectroscopy. J Biotechnol 2018; 288:15–22. doi: 10.1016/J.JBIOTEC.2018.10.003.
Andris S, Wendeler M, Wang X, Hubbuch J. Multi-step high-throughput conjugation platform for the development of antibody-drug conjugates. J Biotechnol 2018; 278:48–55. doi: 10.1016/j.jbiotec.2018.05.004.
Hämmerling F, Ladd Effio C, Andris S, Kittelmann J, Hubbuch J. Investigation and prediction of protein precipitation by polyethylene glycol using quantitative structure–activity relationship models. J Biotechnol 2017; 241. doi: 10.1016/j.jbiotec.2016.11.014.
Talks
Andris S, Wendeler M, Hubbuch J, Establishing a High-throughput Process Development Platform for an Antibody Conjugation Process, HTPD 2017, Toledo, Spain.
Poster
ESBES 2018, Lisbon, Portugal
ACS Spring Meeting 2018, New Orleans, LA, USA