CV and Publications

Scientific CV

04/2016 - now	PhD student at the Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute of Technology (KIT)

12/2015 - 02/2016	Scientific assistant: stability research of highly concentrated monoclonal antibody solutions with the help of rheological measurements and structural anlaysis Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT

05/2015 - 11/2015	Master thesis: Comprehensive study on mAb phase behavior and solution characteristics with the help of rheological methods, dynamic light and fluorescence measurements Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT in cooperation with Synthon Biopharmaceuticals BV Nijmegen, Netherlands

07/2014 - 03/2015	Research assistant: mentoring of students and protein viscosity studies Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT

10/2013 - 03/2014	Internship at Sartorius Stedim Biotech GmbH Characterization of virus filter units for application in down scale processes

04/2013 - 09/2013	Bachelor thesis: Examination of α-Lactalbumin phase behavior with the focus on isoeletric precipitation Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, KIT

12/2010 - 12/2012	Research assistant: chemical, toxicological, microbiological testing, groundwater sampling and luminescent bacteria inhibition test Water Technology Center Karlsruhe (TZW)

10/2010 - 11/2015	Studies of Bioengineering at Karlsruhe Institute of Technology (KIT)

Research Projects

Protein stability studies considering behavior at low temperatures.

Publications

Articles

K.C. Bauer, S. Suhm, A.K. Wöll, J. Hubbuch, Impact of additives on the formation of protein aggregates and viscosity in concentrated protein solutions, Journal of Pharmaceutics (2016), https://doi.org/10.1016/j.ijpharm.2016.11.009

M.-T. Schermeyer, A.K. Wöll, B. Kokke, M. Eppink, J. Hubbuch, Characterization of highly concentrated antibody solution - A toolbox for the description of protein long-term solution stability, Journal mAbs (2017), https://doi.org/10.1080/19420862.2017.1338222

A.K. Wöll, J. Schütz, J. Zabel, J. Hubbuch Analysis of phase behavior and morphology during freeze-thaw applications, Journal of Pharmaceutics (2018), https://doi.org/10.1016/j.ijpharm.2018.11.047

Talks

A. Wöll, M. Desombre, L. Enghauser, J. Hubbuch, Influence of Different Freeze and Thaw Ramps on the Phase Behavior of Lysozyme from Chicken Egg White, ACS Spring Meeting 2018, New Orleans, 22. März 2018