CV and Publications

Scientific CV

05/2020 - 05/2024	PhD student at the Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute for Technology (KIT)
03/2019 - 04/2020	Consultant in Process Engineering, Unit Pharma/Biotech at io-consultants GmbH & Co. KG, Heidelberg
05/2018 - 11/2018	Master thesis: Start-up of a laboratory apparatus for integrated particle generation and separation
	Institute of Mechanical Process Engineering and Mechanics, Working group: Process Machines (VM), Karlsruhe Institute for Technology (KIT)
09/2017 - 03/2018	Internship in Downstream Development at Roche Diagnostics GmbH, Penzberg
	Work: Establishing a method for automated liquid class optimization for high viscous protein solutions using DoE
02/2017 - 05/2017	Erasmus exchange semester at the Technical University of Denmark (DTU), Lyngby, Copenhagen
10/2015 - 11/2018	Studies of Chemical Engineering (M.Sc.), Karlsruhe Institute for Technology (KIT)
06/2015 - 08/2015	Bachelor thesis: Investigation and Optimization of the Interaction between Human IgG and Weak Cation Exchange Membranes
	University of Waterloo, Ontario, Canada in cooperation with the Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering, Karlsruhe Institute for Technology (KIT)
11/2013 - 06/2015	Various jobs as student assistant: Tutor for technical mechanics I and III (Institute of Mechanical Process Engineering and Mechanics at KIT) and scientific assistant in robotic liquid handling and protein precipitation (Institute of Process Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering at KIT)
11/2012 - 10/2015	Studies of Bioengineering (B.Sc.), Karlsruhe Institute for Technology (KIT)

Research Projects

Advanced methods for modelling conjugation at process scale

Publications

Paper

Weggen JT, Seidel J, Bean R, Wendeler M and Hubbuch J (2023) Kinetic studies and CFD-based reaction modeling for insights into the scalability of ADC conjugation reactions. Front. Bioeng. Biotechnol. 11:1123842. https://dx.doi.org/10.3389/fbioe.2023.1123842.

Schiemer, R., Weggen, J. T., Schmitt, K. M., & Hubbuch, J. (2023). An adaptive soft‐sensor for advanced real‐time monitoring of an antibody‐drug conjugation reaction. Biotechnology and Bioengineering, 1–15. https://doi.org/10.1002/bit.28428

Talks

J. Weggen, R. Schiemer, K. Schmitt, J. Hubbuch. An adaptive soft-sensor for advanced real-time monitoring of an antibody-drug conjugation reaction, ACS Fall, San Francisco, USA, August 17, 2023.

Poster

J. Weggen, R. Schiemer, K. Schmitt, J. Hubbuch. Optimal State Estimation of an ADC Conjugation Reaction Using an Extended Kalman Filter, 40th International Symposium on the Separation of Proteins, Peptides & Polynucleotides, November 9, 2021.