CV and Publications

Scientific CV

10/2024 – now	PhD student Institute of Engineering in Life Sciences, Section IV: Biomolecular Separation Engineering Karlsruhe Institute of Technology (KIT)
04/2022 – 09/2024	Process Specialist BioPharma Operations/ Downstream Manufacturing Boehringer Ingelheim
10/2021 – 03/2022	Master’s thesis: Application of mechanistic chromatography modelling for multimodal antibody purification Bioprocess Development Biologicals/ Downstream Processing Boehringer Ingelheim
04/2021 – 09/2021	Internship: Establishing a High-Throughput Process Development Platform Bioprocess Development Biologicals/ Downstream Processing Boehringer Ingelheim
10/2019 – 03/2022	M.Sc. Industrial Biotechnology Technical University of Munich (TUM)
05/2019 – 07/2019	Bachelor’s thesis: Establishing a chemical proteomics assay for target identification of irreversible BTK inhibitors Chair of Proteomics and Bioanalytics Technical University of Munich (TUM)
08/2018 – 09/2018	Internship: Selectivity profiling of drugs in cancer research Chair of Proteomics and Bioanalytics Technical University of Munich (TUM)
10/2016 – 09/2019	B.Sc. Molecular Biotechnology Technical University of Munich (TUM)

Research Projects

Combining PAT and mechanistic/statistical modelling for industrial processes

Publications

Papers

R. Hess, J. Faessler, D. Yun, A. Mama, D. Saleh, J. H. Grosch, G. Wang, T. Schwab, J. Hubbuch, Predicting multimodal chromatography of therapeutic antibodies using multiscale modeling., Journal of chromatography. A 1718 (2024), https://doi.org/10.1016/j.chroma.2024.464706.
R. Hess, J. Faessler, D. Yun, D. Saleh, J. H. Grosch, T. Schwab, J. Hubbuch, Antibody sequence-based prediction of pH gradient elution in multimodal chromatography., Journal of chromatography. A 1711 (2023), https://doi.org/10.1016/j.chroma.2023.464437.
R. Hess, D. Yun, D. Saleh, T. Briskot, J. H. Grosch, G. Wang, T. Schwab, J. Hubbuch, Standardized method for mechanistic modeling of multimodal anion exchange chromatography in flow through operation., Journal of chromatography. A 1690 (2023), https://doi.org/10.1016/j.chroma.2023.463789.