Lebenslauf und Publikationen

Scientific CV

08/2009 - now	Ph.D. student, Institute of Engineering in Life Sciences, KIT
09/2008 – 12/2008	Industriepraktikum bei Genentech Inc., San Francisco, USA High throughput screening of chromatographic resins Evaluation of an alternative method to design experiments
08/2008 – 09/2008	Hilfswissenschaftliche Tätigkeit: „In-silico-Analyse eines genetischen Algorithmus zur Prozessoptimierung“ Institut für Bio- und Lebensmitteltechnik, Universität Karlsruhe (TH)
01/2008 – 07/2008	Diplomarbeit: „Optimierung eines industriellen Aufreinigungsprozesses für monoklonale Antikörper mittels intelligenten, roboterbasierten Hochdurchsatzverfahren“ Institut für Biotechnologie II, Forschungszentrum Jülich Institut für Bio- und Lebensmitteltechnik, Universität Karlsruhe (TH)
05/2006 – 09/2006	Studienarbeit: “Fabrication of dense magnetic pellicular support customized for liquid magnetically stabilized fluidized bed adsorption” Department of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, USA
10/2005 – 03/2006	Industriepraktikum bei Lonza AG, Visp, CH Prozessentwicklung Fed-Batch Fermentation
10/2002 – 07/2008	Studium des Bioingenieurwesens, Universität Karlsruhe (TH)

Research Projects

Predictive Tools in Protein Chromatography: Extension and Optimization of a Molecular Modeling Approach

Publikationen

Poster

von Lieres, E.; Diederich, P.; Siudak, A.; Susanto, A.; Treier, K.; Hubbuch, J.
Optimization of High Throughput Process Optimization
Recovery XIII (Quebec), June 22–27, 2008.

Treier, K.; Diederich, P.; Susanto, A.; Siudak, A.; von Lieres, E.; Hubbuch, J.
High Throughput Downstream Process Development: Optimization of a Cation Exchange Chromatography Step
ISPPP (Baden-Baden), September 21-24, 2008.

P. Diederich, F. Hämmerling, J. Hubbuch (2011).
High Throughput Screening of Aqueous Two-Phase Systems for the Purification of Hen’s Egg White Protein Avidin;
GVC/DECHEMA – Congress, Potsdam, GER

P. Diederich, J. Hubbuch (2011).
Error Estimation for High Throughput Column Chromatography Processes on a Liquid Handling Station;
European Congress on Applied Biotechnology, Berlin, GER

P. Diederich, J. Hubbuch (2010).
Fast Analytical Techniques to complement High Throughput Downstream Process Development- Case Study: Analysis of Hen Egg Proteins using LabChip® and (U)HPLC;
HTPD10, Krakau, Poland

Paper

Patrick Diederich, Sigrid K. Hansen, Stefan A. Oelmeier, Bianca Stolzenberger, Jürgen Hubbuch.
A Sub-Two Minutes Method for Monoclonal Antibody-Aggregate Quantification using Parallel Interlaced Size Exclusion High Performance Liquid Chromatography,
Journal of Chromatography A, 1218(50), pp. 9010-9018 – 2011.

K. Treier, S. Hansen, C. Richter, P. Diederich, J. Hubbuch, P. Lester.
High-throughput methods for miniaturization and automation of monoclonal antibody purification processes,
Biotechnology Progress, 28 (2012) 723-732

Katrin Treier, Annette Berg, Patrick Diederich, Katharina Lang, Anna Osberghaus, Florian Dismer, Jürgen Hubbuch,
Examination of a genetic algorithm for the application in high-throughput downstream process development,
Biotechnology Journal (2012), 7(10), 1203-1215

Presentations

P. Diederich, A. Osberghaus, J. Hubbuch (2012).
Error Analysis & Characterization of µL-scale Column Chromatography performed on Liquid Handling Stations;
HTPD12, Avignon, France

P. Diederich, S. K. Hansen, B. Maiser, N. Schnabel (2011).
A-Mab: a Case Study in Bioprocess Development
Downstream Days Summer School, Wetter a. d. Ruhr, Germany, 2011

P. Diederich, A. Osberghaus, J. Hubbuch (2012).
Aspects on Data Quality of High Throughput Column Chromatography; 8^th international PhD Seminar on Preparative Chromatography,
Freudenstadt-Lauterbad, Germany

P. Diederich, J. Hubbuch (2011).
High Throughput Process Development.
GE healthcare/Sanofi-Aventis Äkta UserClub, Frankfurt a. M., Germany